But the 52-year-old, who returned to the club in 2013, was left with egg on his face as the Blues lost 2-1 at home to south London rivals Crystal Palace.
Stamford Bridge has been a fortress under Mourinho.
In total, he had won 76, drawn 22 and lost only one of 99 Premier League home games in the Chelsea hot seat until, that is, last weekend.
The last Premier League game that the Blues lost at home was in April last year, when bottom club Sunderland claimed a shock 2-1 win.
So how does Mourinho’s home record compare to other Premier League bosses?
Mourinho has won 250 points in a hundred games so far, and the statistics show his tally is the best by a considerable margin. In second place is the legendary Sir Alex Ferguson who accrued 234 points in his first hundred Premier League home games at Old Trafford, tasting defeat on four more occasions than Mourinho.
Rafael Benitez is third on 231 from his time at Liverpool, where he developed a bitter rivalry with Mourinho before a brief stint as ‘interim’ Chelsea manager in 2012/13.
Rock solid home form has been the foundation of Mourinho’s success throughout his managerial career.
Remarkably, he has only lost five of 192 home games in the Premier League (England), Seria A (Italy) and La Liga (Spain) with Chelsea, Inter Milan and Real Madrid combined. José Mourinho is also in hot water for his ruthless treatment of club doctor Eva Carneiro.
FIFA are to discuss the issue at a high-level medical summit next month.
Carneiro infuriated Mourinho when she rushed on to the pitch to treat Eden Hazard in the club’s opening Premier League game against Swansea, leaving Chelsea - who were already down to 10 men - vulnerable defensively.
The doctor has since been stripped of first-team duties and is no longer involved at training sessions, on match days or in the team hotel. The situation has concerned FIFA medical committee chairman Michel D’Hooghe strongly enough for him to want to debate whether FIFA need to issue directives over a team doctor’s code of conduct.